Inherited Level of Risk: DNA-based Evaluations for Common Disorders

Common health conditions in adults involve contributions from a number of essentially normal genes that differ slightly from person to person. Mendelian mutations are uncommon. For example, breast cancer does not usually involve the BRCA1 gene mutation; Alzheimer's disease is almost never is due to APP, PSEN1 or PSEN2 mutations.

Our evaluations consider a number of genes in order to estimate your level of risk either very low, low, moderate or high. Your risk is compared to the population, as a percentage.

• Alzheimer's Gene-Gene Panel (9 genes, including APOE)
• Breast Cancer Gene-Gene Panel (6 genes)
• Heart Attack Gene-Gene Panel (6 genes)

The following are single gene tests:

• Parkinson's Disease LRRK2 Signature identifies whether or not you have inherited a high risk genetic signature in the LRRK2 gene found in a third of patients. This signature is much more common than the p.G2019S mutation.
• Alzheimer's Disease Gene APOE identifies your level of risk for AD, cognitive decline & memory impairment based on APOE genotype.